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DTSTART:20190331T030000
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DTSTART:20191027T020000
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DTSTAMP:20200331T192911Z
UID:BF99CBCB-4EE1-43DD-8DD1-F2EF9B5DF5D0
DTSTART;TZID=Europe/Zurich:20190524T151500
DTEND;TZID=Europe/Zurich:20190524T170000
DESCRIPTION:The first published work on closed-loop control of anesthesia a
 uthored by Mayo\, Bickford and Faulconer dates back to 1950. However\, fee
 dback\ncontrol of anesthesia has yet to become adopted for clinical use de
 spite the fact that since 1950\, and especially since the availability of 
 depth-ofhypnosis\nmonitors many systems have been developed and clinically
  tested. For clinical adoption to take place\, benefits to the patient hav
 e to be\ndemonstrated while patient safety has to be guaranteed. This pres
 entation will focus on the engineering design process that can ensure pati
 ent safety\nby design. A major characteristic of the anesthesia closed-loo
 p control problem is the significant inter and intra-patient variability a
 nd that under such\ncircumstances\, the control system has to perform adeq
 uately and safely for a patient it has never seen and with very limited le
 arning opportunity.\nThis is why it is crucial for such systems to be desi
 gned by expert control engineers well versed in robust control theory. I w
 ill briefly describe the\ntheory of robust control and demonstrate its use
  for closed-loop anesthesia in order to guarantee closed-loop stability an
 d a minimum level of performance\nacceptable to the clinician. Furthermore
 \, the system has to be able to handle safely a number of exceptions with 
 well-designed fallback\nmodes. This is where the field of safety-preservin
 g control\, a concept developed for aeronautic applications\, can provide 
 a number of attractive\nsolutions. This will be demonstrated through work 
 performed at the University of British Columbia when developing our closed
 -loop TIVA control\nsystem\, iControl. Finally\, because the anesthesiolog
 ist will remain in the loop and has to be able to take over in a safe mann
 er should the need arise\,\nthe Human-Computer Interaction (HCI) aspects h
 ave to be carefully studied and designed. I will cover some of our nascent
  work on this topic\, also\ninspired by aeronautics applications.\n\nCo-sp
 onsored by: ETH Zürich - Department of Health Sciences and Technology\n\n
 Speaker(s): Prof. Dr. Guy A. Dumont\, \n\nRoom: G3\, Bldg: HG\, Rämistras
 se 101\, Zürich\, Switzerland\, Switzerland\, 8092 
LOCATION:Room: G3\, Bldg: HG\, Rämistrasse 101\, Zürich\, Switzerland\, S
 witzerland\, 8092 
ORGANIZER:walter.karlen@hest.ethz.ch
SEQUENCE:1
SUMMARY:Towards safe closed-loop control of anesthesia
URL;VALUE=URI:https://events.vtools.ieee.org/m/228248
X-ALT-DESC:Description: &lt;br /&gt;&lt;p&gt;The first published work on closed-loop co
 ntrol of anesthesia authored by Mayo\, Bickford and Faulconer dates back t
 o 1950. However\, feedback&lt;br /&gt;control of anesthesia has yet to become ad
 opted for clinical use despite the fact that since 1950\, and especially s
 ince the availability of depth-ofhypnosis&lt;br /&gt;monitors many systems have 
 been developed and clinically tested. For clinical adoption to take place\
 , benefits to the patient have to be&lt;br /&gt;demonstrated while patient safet
 y has to be guaranteed. This presentation will focus on the engineering de
 sign process that can ensure patient safety&lt;br /&gt;by design. A major charac
 teristic of the anesthesia closed-loop control problem is the significant 
 inter and intra-patient variability and that under such&lt;br /&gt;circumstances
 \, the control system has to perform adequately and safely for a patient i
 t has never seen and with very limited learning opportunity.&lt;br /&gt;This is 
 why it is crucial for such systems to be designed by expert control engine
 ers well versed in robust control theory. I will briefly describe the&lt;br /
 &gt;theory of robust control and demonstrate its use for closed-loop anesthes
 ia in order to guarantee closed-loop stability and a minimum level of perf
 ormance&lt;br /&gt;acceptable to the clinician. Furthermore\, the system has to 
 be able to handle safely a number of exceptions with well-designed fallbac
 k&lt;br /&gt;modes. This is where the field of safety-preserving control\, a con
 cept developed for aeronautic applications\, can provide a number of attra
 ctive&lt;br /&gt;solutions. This will be demonstrated through work performed at 
 the University of British Columbia when developing our closed-loop TIVA co
 ntrol&lt;br /&gt;system\, iControl. Finally\, because the anesthesiologist will 
 remain in the loop and has to be able to take over in a safe manner should
  the need arise\,&lt;br /&gt;the Human-Computer Interaction (HCI) aspects have t
 o be carefully studied and designed. I will cover some of our nascent work
  on this topic\, also&lt;br /&gt;inspired by aeronautics applications.&lt;/p&gt;
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