BEGIN:VCALENDAR VERSION:2.0 PRODID:IEEE vTools.Events//EN CALSCALE:GREGORIAN BEGIN:VTIMEZONE TZID:Canada/Eastern BEGIN:DAYLIGHT DTSTART:20200308T030000 TZOFFSETFROM:-0500 TZOFFSETTO:-0400 RRULE:FREQ=YEARLY;BYDAY=2SU;BYMONTH=3 TZNAME:EDT END:DAYLIGHT BEGIN:STANDARD DTSTART:20201101T010000 TZOFFSETFROM:-0400 TZOFFSETTO:-0500 RRULE:FREQ=YEARLY;BYDAY=1SU;BYMONTH=11 TZNAME:EST END:STANDARD END:VTIMEZONE BEGIN:VEVENT DTSTAMP:20201006T230015Z UID:AA45E15D-D381-4306-B161-840A0F511FCF DTSTART;TZID=Canada/Eastern:20200528T150000 DTEND;TZID=Canada/Eastern:20200528T160000 DESCRIPTION:Virtual seminar of the Quebec IEEE CAS/EMB Chapter:\n\nGastroin testinal (GI) motility is coordinated by underlying bio-electrical events known as slow waves. High-resolution (HR) mapping of the slow waves has be come a fundamental tool for accurately defining electrophysiological prope rties in gastroenterology\, including dysrhythmias in gastric disorders su ch as gastroparesis\, chronic nausea and unexplained vomiting\, and functi onal dyspepsia. Currently\, HR mapping is achieved via acquisition of slow waves taken directly from the serosa of fasted subjects undergoing invasi ve abdominal surgery.\nAs in cardiac electrophysiology\, implantable pulse generators have been used for stimulating the stomach. Conventionally\, t wo types of pulses have been applied for potential therapeutic effects for gastroparesis: short pulses (high frequency/low energy) and long pulses ( low frequency/high energy). Low-energy stimulation is typically delivered with a pulse-width in the order of a few hundred microseconds\, at frequen cies ranging from 5 to 100 Hz\, and may improve symptoms such as nausea\, vomiting\, and bloating. High-energy stimulation (or pacing) is typically delivered with a pulse-width in the order of milliseconds (10-600 ms)\, at frequencies akin to the natural gastric frequency (i.e.\, 3 cpm). High-en ergy stimulation has demonstrated potential to pace slow waves and improve motility. Due to high energy consumption the latter stimulation method ha s not been widely used.\nWe have developed novel bioelectronics that can b e used for HR mapping and modulating of the gut activity in small and larg e animals. These devices are implantable and can wirelessly communicate wi th a computer station to visualize the recorded signals in real time. Oper ator can also use the graphical user interface on the computer to modify t he electrical stimulation parameters. The implant can be wirelessly rechar ged through inductive coupling transmission. The system has been validated in small and large animals. We have been able to map the stomach activity wirelessly in high resolution\, and modulate the stomach activity in vari ous paces. Also\, we have used the system –with lower number of channels – to record slow wave signals from patients with gastroparesis. We are p lanning to integrate the mapping and modulating technologies into a closed -loop therapy\, and to translate the developed technologies to human.\n\nS peaker(s): Dr Aydin Farajidavar\, \n\nAgenda: \nSéminar: 45 min\n\nQ&A: 1 5 min\n\nRoom: Virtual\, Bldg: ZOOM\, https://us02web.zoom.us/j/8507064604 5\, Quebec City\, Quebec\, Canada\, G1V 0A6 LOCATION:Room: Virtual\, Bldg: ZOOM\, https://us02web.zoom.us/j/85070646045 \, Quebec City\, Quebec\, Canada\, G1V 0A6 ORGANIZER:benoit.gosselin@gel.ulaval.ca SEQUENCE:4 SUMMARY:Electroceuticals for Mapping and Modulating Gut Activity: Towards C losed-loop Management of Functional Gastrointestinal Disorders URL;VALUE=URI:https://events.vtools.ieee.org/m/231818 X-ALT-DESC:Description: <br /><p>Virtual seminar of the Quebec IEEE CAS/EMB Chapter:</p>\n<p>Gastrointestinal (GI) motility is coordinated by underly ing bio-electrical events known as slow waves. High-resolution (HR) mappin g of the slow waves has become a fundamental tool for accurately defining electrophysiological properties in gastroenterology\, including dysrhythmi as in gastric disorders such as gastroparesis\, chronic nausea and unexpla ined vomiting\, and functional dyspepsia. Currently\, HR mapping is achiev ed via acquisition of slow waves taken directly from the serosa of fasted subjects undergoing invasive abdominal surgery.<br />As in cardiac electro physiology\, implantable pulse generators have been used for stimulating t he stomach. Conventionally\, two types of pulses have been applied for pot ential therapeutic effects for gastroparesis: short pulses (high frequency /low energy) and long pulses (low frequency/high energy). Low-energy stimu lation is typically delivered with a pulse-width in the order of a few hun dred microseconds\, at frequencies ranging from 5 to 100 Hz\, and may impr ove symptoms such as nausea\, vomiting\, and bloating. High-energy stimula tion (or pacing) is typically delivered with a pulse-width in the order of milliseconds (10-600 ms)\, at frequencies akin to the natural gastric fre quency (i.e.\, 3 cpm). High-energy stimulation has demonstrated potential to pace slow waves and improve motility. Due to high energy consumption th e latter stimulation method has not been widely used.<br />We have develop ed novel bioelectronics that can be used for HR mapping and modulating of the gut activity in small and large animals. These devices are implantable and can wirelessly communicate with a computer station to visualize the r ecorded signals in real time. Operator can also use the graphical user int erface on the computer to modify the electrical stimulation parameters. Th e implant can be wirelessly recharged through inductive coupling transmiss ion. The system has been validated in small and large animals. We have bee n able to map the stomach activity wirelessly in high resolution\, and mod ulate the stomach activity in various paces. Also\, we have used the syste m &ndash\;with lower number of channels&ndash\; to record slow wave signal s from patients with gastroparesis. We are planning to integrate the mappi ng and modulating technologies into a closed-loop therapy\, and to transla te the developed technologies to human.</p><br /><br />Agenda: <br /><p>S& eacute\;minar: 45 min</p>\n<p>Q&amp\;A: 15 min</p> END:VEVENT END:VCALENDAR