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DTSTART:20220313T030000
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DTSTART:20221106T010000
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DTSTAMP:20220516T170619Z
UID:2C01F71A-CEB2-45C1-AE2D-AA355F6639F3
DTSTART;TZID=America/Denver:20220506T110000
DTEND;TZID=America/Denver:20220506T121500
DESCRIPTION:Current microMRI uses large superconducting magnets (&gt; 7T) and 
 can obtain a resolution of approximately 2 to 20 micrometers. However\, mi
 croMRI systems cannot resolve cells or compete with optical techniques req
 uired for pathology and personalized medicine applications. Point-of-use h
 yperpolarization systems can provide both enhanced signal and contrast ena
 bling microMRI of small samples such as tumor biopsies and patient derived
  organoids used for\ntherapeutic evaluation.\nHere\, I present the develop
 ment of a novel table-top microMRI system that uses integrated point-of-us
 e solid-state water-proton hyperpolarization systems that rely on spintron
 ic concepts. The system operates at 135 mT with the nuclear magnetic reson
 ance (NMR) and ferromagnetic resonance (FMR)-based hyperpolarization syste
 ms running at ~6 MHz and ~10 GHz\, respectively. The hyperpolarizer operat
 es at room temperature and low field and is much smaller and simpler than 
 other existing hyperpolarization systems. The mode structure of the FMR fi
 lm can be complex and needs to be understood to optimize spin transfer. I 
 will discuss spin transport and spin-electrochemistry of ferromagnetic fil
 ms interacting with proton spins in biologic solutions. The surface spin c
 hemistry and transport is complex and the essential component of this tech
 nology. I will also discuss the design of micromagnets\, compact gradients
 \, FPGA based console\, and compact microwave systems which are required t
 o enable the fabrication of a low-cost small footprint table-top MRI.\n\nC
 o-sponsored by: UCCS\n\nSpeaker(s): Stephen Russek\, \n\nRoom: A204\, Bldg
 : Osborne Center for Science and Engineering\, 1420 Austin Bluffs Pkwy\, C
 olorado Springs\, Colorado\, United States\, 80918\, Virtual: https://even
 ts.vtools.ieee.org/m/313830
LOCATION:Room: A204\, Bldg: Osborne Center for Science and Engineering\, 14
 20 Austin Bluffs Pkwy\, Colorado Springs\, Colorado\, United States\, 8091
 8\, Virtual: https://events.vtools.ieee.org/m/313830
ORGANIZER:dbozhko@uccs.edu
SEQUENCE:4
SUMMARY:Table Top microMRI for Cell Imaging
URL;VALUE=URI:https://events.vtools.ieee.org/m/313830
X-ALT-DESC:Description: &lt;br /&gt;&lt;p&gt;Current microMRI uses large superconductin
 g magnets (&amp;gt\; 7T) and can obtain a resolution of approximately 2 to 20 
 micrometers. However\, microMRI systems cannot resolve cells or compete wi
 th optical techniques required for pathology and personalized medicine app
 lications. Point-of-use hyperpolarization systems can provide both enhance
 d signal and contrast enabling microMRI of small samples such as tumor bio
 psies and patient derived organoids used for&lt;br /&gt;therapeutic evaluation.&amp;
 nbsp\;&lt;br /&gt;Here\, I present the development of a novel table-top microMRI
  system that uses integrated point-of-use solid-state water-proton hyperpo
 larization systems that rely on spintronic concepts. The system operates a
 t 135 mT with the nuclear magnetic resonance (NMR) and ferromagnetic reson
 ance (FMR)-based hyperpolarization systems running at ~6 MHz and ~10 GHz\,
  respectively. The hyperpolarizer operates at room temperature and low fie
 ld and is much smaller and simpler than other existing hyperpolarization s
 ystems. The mode structure of the FMR film can be complex and needs to be 
 understood to optimize spin transfer. I will discuss spin transport and sp
 in-electrochemistry of ferromagnetic films interacting with proton spins i
 n biologic solutions. The surface spin chemistry and transport is complex 
 and the essential component of this technology. I will also discuss the de
 sign of micromagnets\, compact gradients\, FPGA based console\, and compac
 t microwave systems which are required to enable the fabrication of a low-
 cost small footprint table-top MRI.&lt;/p&gt;
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