BEGIN:VCALENDAR VERSION:2.0 PRODID:IEEE vTools.Events//EN CALSCALE:GREGORIAN BEGIN:VTIMEZONE TZID:America/Chicago BEGIN:DAYLIGHT DTSTART:20250309T030000 TZOFFSETFROM:-0600 TZOFFSETTO:-0500 RRULE:FREQ=YEARLY;BYDAY=2SU;BYMONTH=3 TZNAME:CDT END:DAYLIGHT BEGIN:STANDARD DTSTART:20251102T010000 TZOFFSETFROM:-0500 TZOFFSETTO:-0600 RRULE:FREQ=YEARLY;BYDAY=1SU;BYMONTH=11 TZNAME:CST END:STANDARD END:VTIMEZONE BEGIN:VEVENT DTSTAMP:20250722T153658Z UID:641A04E5-53A9-478D-BD68-AB990531B99B DTSTART;TZID=America/Chicago:20250715T120000 DTEND;TZID=America/Chicago:20250715T130000 DESCRIPTION:If interested in applying for a CE\, Fill out [this Form](https ://forms.gle/9q89ogEgrNAjY3sE8) after the Session\n\nThe biggest barriers to POC diagnostics are cost\, time and performance. This holds true in bot h wealthy and developing countries. The COVID pandemic has shown us that w hile there are many promising diagnostic technologies\, cheap and easy col orimetric LFAs that can be manufactured and used worldwide remained the do minant POC test despite lower performance and slower response than more co stly confirmatory lab tests such as PCR. In short\, there remains a need f or a cheap\, easy and quick test that can be offered at the POC but approa ches lab based diagnostic performance (sensitivity and quantitation). By s imply adding a reading step onto colorimetric LFAs handheld LED TCA reader s can fill this role in a cost-effective and scalable manner to improve PO C diagnostics for seasonal\, endemic and pandemic diseases worldwide. To a ddress this we have developed a low-cost\, handheld\, LED-based thermal co ntrast assay (TCA) reader for colorimetric lateral flow assays (LFA). TCA utilizes the irradiation of LFAs and resulting temperature increases aroun d the test line as a quantitative readout to approach ELISA sensitivities without the need for additional modalities or steps to increase sensitivit y such as fluorescence or luminescence. TCA has until now been limited to more costly bench top readers for research use. The implementation of LED- based TCA allows a cheap\, robust and easy approach to dramatically improv e sensitivity and quantitation of LFA diagnostics at the POC.\n\nProf. Joh n Bischof. is a Distinguished McKnight University Professor and a faculty member in the Departments of Mechanical Engineering and Biomedical Enginee ring. He serves as Director of both the University of Minnesota Institute for Engineering in Medicine and the NSF Engineering Research Center for Ad vanced Technologies for Preservation of Biological Systems. In addition\, Dr. Bischof currently holds the Medtronic-Bakken Endowed Chair for Enginee ring in Medicine.\n\nProf. Bischof is the Office of Academic Clinical Affa irs (OACA) Sr. Research Advisor for Office of Discovery and Translation (O DAT) Grant Programs\, a role that includes serving as faculty lead for the Minnesota Partnership for Biotechnology and Medical Genomics\, Regenerati ve Medicine Minnesota\, and the OACA Faculty Research Development funding programs.\n\nProf. Bischof is an expert in thermal bioengineering\, includ ing cryobiology (low temperature biology) and hyper-thermic biology\, both of which have broad application in cancer and cardiovascular therapeutics \, diagnostics\, and cryopreservation. His work with some of the leading b iomedical and device companies has informed numerous thermal- and energy-b ased therapeutic device designs and operations for prostate\, kidney\, and pancreatic cancer\, benign prostate hypertrophy\, and Atrial fibrillation . His lab has also pioneered photothermal technology that allows low-sensi tivity point-of-care lateral flow diagnostic assays to rival laboratory te sts in performance and sensitivity at a fraction of the cost\, time\, and training. Finally\, his lab has provided new technology and protocols for cryopreservation of organisms (zebrafish\, Drosophila\, and coral)\, tissu es (including slices and organoids - pancreatic islets)\, and whole organs that helped launch a new NSF ERC (Advanced Technologies for the Preservat ion of Biological Systems – ATP-Bio.org).\n\nCo-sponsored by: Internatio nal Institute for Biosensing\, University of Minnesota\n\nSpeaker(s): John Bischof\n\nVirtual: https://events.vtools.ieee.org/m/491956 LOCATION:Virtual: https://events.vtools.ieee.org/m/491956 ORGANIZER:patricia.khashayar@ieee.org SEQUENCE:10 SUMMARY:A Breakthrough in Colorimetric Lateral Flow Diagnostics: An LED-Bas ed Handheld Thermal Contrast Reader URL;VALUE=URI:https://events.vtools.ieee.org/m/491956 X-ALT-DESC:Description: <br /><p><strong>If interested in applying for a CE \, Fill out <a href="https://forms.gle/9q89ogEgrNAjY3sE8" target="_blank" rel="noopener">this Form</a> after the Session</strong></p>\n<p>The bigges t barriers to POC diagnostics are cost\, time and performance. This holds true in both wealthy and developing countries. The COVID pandemic has show n us that while there are many promising diagnostic technologies\, cheap a nd easy colorimetric LFAs that can be manufactured and used worldwide rema ined the dominant POC test despite lower performance and slower response t han more costly confirmatory lab tests such as PCR. In short\, there remai ns a need for a cheap\, easy and quick test that can be offered at the POC but approaches lab based diagnostic performance (sensitivity and quantita tion).&nbsp\; By simply adding a reading step onto colorimetric LFAs handh eld LED TCA readers can fill this role in a cost-effective and scalable ma nner to improve POC diagnostics for seasonal\, endemic and pandemic diseas es worldwide. To address this we have developed a low-cost\, handheld\, LE D-based thermal contrast assay (TCA) reader for colorimetric lateral flow assays (LFA). TCA utilizes the irradiation of LFAs and resulting temperatu re increases around the test line as a quantitative readout to approach EL ISA sensitivities without the need for additional modalities or steps to i ncrease sensitivity such as fluorescence or luminescence. TCA has until no w been limited to more costly bench top readers for research use.&nbsp\; T he implementation of LED-based TCA allows a cheap\, robust and easy approa ch to dramatically improve sensitivity and quantitation of LFA diagnostics at the POC.&nbsp\;</p>\n<p>Prof. John Bischof. is a Distinguished McKnigh t University Professor and a faculty member in the Departments of Mechanic al Engineering and Biomedical Engineering. He serves as Director of both t he University of Minnesota Institute for Engineering in Medicine and the N SF Engineering Research Center for Advanced Technologies for Preservation of Biological Systems. In addition\, Dr. Bischof currently holds the Medtr onic-Bakken Endowed Chair for Engineering in Medicine.</p>\n<p>Prof. Bisch of is the Office of Academic Clinical Affairs (OACA) Sr. Research Advisor for Office of Discovery and Translation (ODAT) Grant Programs\, a role tha t includes serving as faculty lead for the Minnesota Partnership for Biote chnology and Medical Genomics\, Regenerative Medicine Minnesota\, and the OACA Faculty Research Development funding programs.</p>\n<p>Prof. Bischof is an expert in thermal bioengineering\, including cryobiology (low temper ature biology) and hyper-thermic biology\, both of which have broad applic ation in cancer and cardiovascular therapeutics\, diagnostics\, and cryopr eservation. His work with some of the leading biomedical and device compan ies has informed numerous thermal- and energy-based therapeutic device des igns and operations for prostate\, kidney\, and pancreatic cancer\, benign prostate hypertrophy\, and Atrial fibrillation. His lab has also pioneere d photothermal technology that allows low-sensitivity point-of-care latera l flow diagnostic assays to rival laboratory tests in performance and sens itivity at a fraction of the cost\, time\, and training. Finally\, his lab has provided new technology and protocols for cryopreservation of organis ms (zebrafish\, Drosophila\, and coral)\, tissues (including slices and or ganoids - pancreatic islets)\, and whole organs that helped launch a new N SF ERC (Advanced Technologies for the Preservation of Biological Systems & ndash\; ATP-Bio.org).</p> END:VEVENT END:VCALENDAR