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DESCRIPTION:Re-engineering the World with Self Assembly\n\n[]\n\nAbstract:\
 n\nNature has evolved to self-assemble complex functional architectures in
  a sustainable bottom-up way. From bacteria to humans\, biological systems
  arise from a common set of atomically precise nanoscale building blocks s
 uch as proteins that give rise to complex functions such as sensing\, comp
 utation\, and actuation.\n\nIn contrast\, most human-made devices are comp
 osed of building blocks with much less precision\, and are assembled throu
 gh a top-down process which is highly inflexible and unsustainable. Drawba
 cks aside\, these devices are highly useful and can often surpass their bi
 ological counterparts (e.g.\, computers playing chess). This success is la
 rgely due to a systematic and modular engineering approach where simple bu
 t well-understood components such as transistors are put together in a pro
 grammable way. Is it possible to develop a new approach to building comple
 x devices that combines the strengths of biomolecular self-assembly and sy
 stematic engineering?\n\nIn this talk I will discuss recent work towards t
 his goal using DNA as a nanoscale\, programmable building block [1-5]. How
 ever\, despite being the most programmable molecule for information proces
 sing\, DNA lacks the basic physical attributes required for building high 
 performance electronic devices.\n\nI will discuss ongoing work towards a n
 ew type of nanoscale building blocks in which DNA can be flexibly replaced
  with other materials such as metals and semiconductors. These nanoscale m
 odules can be designed to self-assemble into a variety of plasmonic\, phot
 onic\, and electronic architectures unattainable with any current nanofabr
 ication techniques. This novel approach integrates the advantages of natur
 al bottom-up assembly and engineered top-down programming and may lead to 
 a host of new intelligent devices for technology and medicine. Two specifi
 c devices we are currently developing in our lab are single photon sensors
  with spectral resolution and electronic sensors for multiplexed detection
  of large biological targets.\n\nReferences:\n\n1. G. Tikhomirov\, S. Hoog
 land\, P. Lee\, A. Fisher\, E.H. Sargent\, S.O. Kelley “DNA-Based Progra
 mming of Quantum Dot Valency\, Self-Assembly\, and Luminescence” Nature 
 Nanotechnology\, 2011\, 485-490\n\n2. G. Tikhomirov\, P. Petersen\, L. Qia
 n “Fractal assembly of micrometre-scale DNA origami arrays with arbitrar
 y patterns” Nature\, 2017\, 67-71\n\n3. G. Tikhomirov\, P. Petersen\, L.
  Qian “Programmable disorder in random DNA tilings” Nature Nanotechnol
 ogy\, 2017\, 251-259\n\n4. P. Petersen\, G. Tikhomirov\, L. Qian. “Infor
 mation-based autonomous reconfiguration in systems of interacting DNA nano
 structures” Nature Communications\, 2018\, 5362\n\n5. G. Tikhomirov\, P.
  Petersen\, L. Qian “Triangular DNA origami tilings” JACS\, 2018\, 173
 61recision manufacturing at the nanoscale faces a fundamental energy bottl
 eneck: achieving the resolution needed for next-generation devices require
 s laser powers so high they severely limit throughput and scalability.\n\n
 Speaker:\n\nGrigory Tikhomirov\n\nAssistant Professor\n\nDepartment of Ele
 ctrical Engineering and Computer Sciences\n\nUC Berkeley\n\nGreg a has lon
 gstanding dream to build systems approaching the complexity of life\, moti
 vated by the realization that incomprehensible natural complexity arises f
 rom comprehensible fundamental laws.\n\nGreg is interested both in underst
 anding the principles required to build such systems as well as in buildin
 g practical devices using these principles.\n\nAGENDA:\n\nThursday Septemb
 er 25\, 2025\n\n11:30 AM: Networking\, Pizza &amp; Drinks\n\nNoon -- 1 pm: Sem
 inar\n\nPlease register on Eventbrite before 9:30 AM on Thursday September
  25\, 2025\n\n$4 IEEE members $6 non IEEE members\n\n(discounts for unempl
 oyed and students )\n\nSee examplesAdd\n\nCo-sponsored by: 636940-Santa Cl
 ara Valley Section Chapter\,EMB18\n\nBldg: ==&gt; Use corner entrance: Kifer 
 Road / San Lucar Court ==&gt; Do not enter at main entrance on Kifer Road\, E
 AG Labs\, 810 Kifer Road\, Sunnyvale\, California\, California\, United St
 ates\, 95051
LOCATION:Bldg: ==&gt; Use corner entrance: Kifer Road / San Lucar Court ==&gt; Do
  not enter at main entrance on Kifer Road\, EAG Labs\, 810 Kifer Road\, Su
 nnyvale\, California\, California\, United States\, 95051
ORGANIZER:G.M.Friedman@ieee.org
SEQUENCE:38
SUMMARY:Re-engineering the World with Self-Assembly
URL;VALUE=URI:https://events.vtools.ieee.org/m/500966
X-ALT-DESC:Description: &lt;br /&gt;&lt;div class=&quot;eds-l-mar-vert-6 eds-l-sm-mar-ver
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 &quot;&gt;\n&lt;h1 class=&quot;event-title css-0&quot;&gt;&lt;strong&gt;Re-engineering the World with Se
 lf Assembly&lt;/strong&gt;&lt;/h1&gt;\n&lt;p&gt;&lt;img src=&quot;https://events.vtools.ieee.org/vto
 ols_ui/media/display/759831d8-da00-45b0-b954-92ed5febb728&quot; alt=&quot;&quot; width=&quot;6
 00&quot; height=&quot;402&quot;&gt;&lt;/p&gt;\n&lt;/div&gt;\n&lt;/div&gt;\n&lt;div class=&quot;eds-l-mar-vert-6 eds-l-
 sm-mar-vert-4 eds-text-bm structured-content-rich-text&quot;&gt;\n&lt;div class=&quot;eds-
 text--left&quot;&gt;\n&lt;p&gt;&amp;nbsp\;&lt;/p&gt;\n&lt;p&gt;&lt;strong&gt;Abstract:&lt;/strong&gt;&lt;/p&gt;\n&lt;h3&gt;Natur
 e has evolved to self-assemble complex functional architectures in a susta
 inable bottom-up way. From bacteria to humans\, biological systems arise f
 rom a common set of atomically precise nanoscale building blocks such as p
 roteins that give rise to complex functions such as sensing\, computation\
 , and actuation.&lt;/h3&gt;\n&lt;h3&gt;In contrast\, most human-made devices are compo
 sed of building blocks with much less precision\, and are assembled throug
 h a top-down process which is highly inflexible and unsustainable. Drawbac
 ks aside\, these devices are highly useful and can often surpass their bio
 logical counterparts (e.g.\, computers playing chess). This success is lar
 gely due to a systematic and modular engineering approach where simple but
  well-understood components such as transistors are put together in a prog
 rammable way. Is it possible to develop a new approach to building complex
  devices that combines the strengths of biomolecular self-assembly and sys
 tematic engineering?&lt;/h3&gt;\n&lt;h3&gt;In this talk I will discuss recent work tow
 ards this goal using DNA as a nanoscale\, programmable building block [1-5
 ]. However\, despite being the most programmable molecule for information 
 processing\, DNA lacks the basic physical attributes required for building
  high performance electronic devices.&lt;/h3&gt;\n&lt;h3&gt;I will discuss ongoing wor
 k towards a new type of nanoscale building blocks in which DNA can be flex
 ibly replaced with other materials such as metals and semiconductors. Thes
 e nanoscale modules can be designed to self-assemble into a variety of pla
 smonic\, photonic\, and electronic architectures unattainable with any cur
 rent nanofabrication techniques. This novel approach integrates the advant
 ages of natural bottom-up assembly and engineered top-down programming and
  may lead to a host of new intelligent devices for technology and medicine
 . Two specific devices we are currently developing in our lab are single p
 hoton sensors with spectral resolution and electronic sensors for multiple
 xed detection of large biological targets.&lt;/h3&gt;\n&lt;h4&gt;&lt;em&gt;References:&lt;/em&gt;&lt;
 /h4&gt;\n&lt;h4&gt;1. G. Tikhomirov\, S. Hoogland\, P. Lee\, A. Fisher\, E.H. Sarge
 nt\, S.O. Kelley &amp;ldquo\;DNA-Based Programming of Quantum Dot Valency\, Se
 lf-Assembly\, and Luminescence&amp;rdquo\;&amp;nbsp\;&lt;em&gt;Nature Nanotechnology\,&amp;n
 bsp\;&lt;/em&gt;2011\, 485-490&lt;/h4&gt;\n&lt;h4&gt;2. G. Tikhomirov\, P. Petersen\, L. Qia
 n &amp;ldquo\;Fractal assembly of micrometre-scale DNA origami arrays with arb
 itrary patterns&amp;rdquo\;&amp;nbsp\;&lt;em&gt;Nature\,&lt;/em&gt;&amp;nbsp\;2017\, 67-71&lt;/h4&gt;\n&lt;
 h4&gt;3. G. Tikhomirov\, P. Petersen\, L. Qian &amp;ldquo\;Programmable disorder 
 in random DNA tilings&amp;rdquo\;&amp;nbsp\;&lt;em&gt;Nature Nanotechnology&lt;/em&gt;\, 2017\
 , 251-259&lt;/h4&gt;\n&lt;h4&gt;4. P. Petersen\, G. Tikhomirov\, L. Qian. &amp;ldquo\;Info
 rmation-based autonomous reconfiguration in systems of interacting DNA nan
 ostructures&amp;rdquo\;&amp;nbsp\;&lt;em&gt;Nature Communications&lt;/em&gt;\, 2018\, 5362&lt;/h4
 &gt;\n&lt;h4&gt;5. G. Tikhomirov\, P. Petersen\, L. Qian &amp;ldquo\;Triangular DNA ori
 gami tilings&amp;rdquo\;&amp;nbsp\;&lt;em&gt;JACS&lt;/em&gt;\, 2018\, 17361recision manufactur
 ing at the nanoscale faces a fundamental energy bottleneck: achieving the 
 resolution needed for next-generation devices requires laser powers so hig
 h they severely limit throughput and scalability.&lt;/h4&gt;\n&lt;p&gt;&lt;img src=&quot;https
 ://events.vtools.ieee.org/vtools_ui/media/display/327c3a26-5247-45e6-95b7-
 9522970bc2ae&quot; width=&quot;798&quot; height=&quot;449&quot;&gt;&lt;/p&gt;\n&lt;h3&gt;Speaker:&lt;/h3&gt;\n&lt;h1&gt;Grigor
 y Tikhomirov&lt;/h1&gt;\n&lt;h3&gt;Assistant Professor&lt;/h3&gt;\n&lt;h3&gt;Department of Electri
 cal Engineering and Computer Sciences&lt;/h3&gt;\n&lt;h3&gt;UC Berkeley&lt;/h3&gt;\n&lt;h3&gt;Greg
  a has longstanding dream to build systems approaching the complexity of l
 ife\, motivated by the realization that incomprehensible natural complexit
 y arises from comprehensible fundamental laws.&lt;/h3&gt;\n&lt;h3&gt;Greg is intereste
 d both in understanding the principles required to build such systems as w
 ell as in building practical devices using these principles.&lt;/h3&gt;\n&lt;h3&gt;&lt;st
 rong&gt;AGENDA:&lt;/strong&gt;&lt;/h3&gt;\n&lt;/div&gt;\n&lt;/div&gt;\n&lt;div class=&quot;eds-l-mar-vert-6 e
 ds-l-sm-mar-vert-4 eds-text-bm structured-content-rich-text&quot;&gt;\n&lt;div class=
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 sListPreview&quot;&gt;\n&lt;div class=&quot;css-1hbyxwu e1pmrtpl0&quot;&gt;\n&lt;p&gt;&lt;strong&gt;Thursday S
 eptember 25&lt;/strong&gt;&lt;strong&gt;\, 2025&lt;/strong&gt;&lt;/p&gt;\n&lt;p&gt;&lt;strong&gt;11:30 AM: Net
 working\, Pizza &amp;amp\; Drinks&lt;/strong&gt;&lt;/p&gt;\n&lt;p&gt;&lt;strong&gt;Noon -- 1 pm: Semin
 ar&lt;/strong&gt;&lt;/p&gt;\n&lt;p&gt;&lt;strong&gt;Please register on Eventbrite before 9:30 AM o
 n&lt;/strong&gt;&lt;strong&gt; Thursday September 25\, 2025&lt;/strong&gt;&lt;/p&gt;\n&lt;p&gt;&lt;strong&gt;$
 4 IEEE members&amp;nbsp\; $6 non IEEE members &lt;/strong&gt;&lt;/p&gt;\n&lt;p&gt;&lt;strong&gt;(disco
 unts for unemployed and students&lt;/strong&gt; )&lt;/p&gt;\n&lt;/div&gt;\n&lt;/div&gt;\n&lt;/div&gt;\n&lt;
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