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DTSTAMP:20251213T125742Z
UID:C389FD33-B187-44AB-8816-04C5A5E8EC56
DTSTART;TZID=Europe/Prague:20250911T140000
DTEND;TZID=Europe/Prague:20250911T150000
DESCRIPTION:Compared to conventional photon-beam radiotherapy\, ion-beam ra
 diotherapy can provide more conformal and focused dose distributions. Howe
 ver\, the steep gradients of such focused dose distributions lead to an in
 creased sensitivity to treatment uncertainties. Therefore\, a method for d
 aily verification of the patient’s anatomy\, tissue composition and the 
 patient positioning is of great interest.\nIn this context\, ion-beam radi
 ography is a promising imaging modality\, since it relies on the same phys
 ical mechanisms as ion-beam therapy does. Furthermore\, the imaging dose c
 an be lowered compared to the conventional x-ray imaging.\nIn this seminar
 \, I will present the current status of our long-standing project on heliu
 m-beam radiography (αRAD) at the German Cancer Research Center and the He
 idelberg Ion-beam Therapy Center (HIT). The experimental work is based on 
 our compact detection system that we exclusively built from Timepix detect
 ors.\nAfter the explanation of basic principles and characteristics of αR
 AD\, the latest results concerning image quality of our quantitative metho
 d for complex objects that mimic the human anatomy will be presented. Furt
 hermore\, the feasibility of using small and low-dose αRads for patient p
 ositioning is discussed and finally an approach to extract depth informati
 on from 2D radiographs\, called 2.5D imaging\, will be introduced.\nGiven 
 the promising results\, next steps towards an envisaged clinical applicati
 on are outlined.\n\nTim Gehrke\n\nIEAP\, CTU in Prague\, Husova 240/5\, Pr
 ague\, Czech Republic\, Czech Republic
LOCATION:IEAP\, CTU in Prague\, Husova 240/5\, Prague\, Czech Republic\, Cz
 ech Republic
ORGANIZER:andre.sopczak@cern.ch
SEQUENCE:4
SUMMARY:Towards accuracy improvements of ion-beam therapy applying helium-b
 eam radiography based on Timepix detectors
URL;VALUE=URI:https://events.vtools.ieee.org/m/522191
X-ALT-DESC:Description: <br /><p>Compared to conventional photon-beam radio
 therapy\, ion-beam radiotherapy can provide more conformal and focused dos
 e distributions. However\, the steep gradients of such focused dose distri
 butions lead to an increased sensitivity to treatment uncertainties. There
 fore\, a method for daily verification of the patient&rsquo\;s anatomy\, t
 issue composition and the patient positioning is of great interest.&nbsp\;
 <br>In this context\, ion-beam radiography is a promising imaging modality
 \, since it relies on the same physical mechanisms as ion-beam therapy doe
 s. Furthermore\, the imaging dose can be lowered compared to the conventio
 nal x-ray imaging.&nbsp\;<br>In this seminar\, I will present the current 
 status of our long-standing project on helium-beam radiography (&alpha\;RA
 D) at the German Cancer Research Center and the Heidelberg Ion-beam Therap
 y Center (HIT). The experimental work is based on our compact detection sy
 stem that we exclusively built from Timepix detectors.&nbsp\;<br>After the
  explanation of basic principles and characteristics of &alpha\;RAD\, the 
 latest results concerning image quality of our quantitative method for com
 plex objects that mimic the human anatomy will be presented. Furthermore\,
  the feasibility of using small and low-dose &alpha\;Rads for patient posi
 tioning is discussed and finally an approach to extract depth information 
 from 2D radiographs\, called 2.5D imaging\, will be introduced.<br>Given t
 he promising results\, next steps towards an envisaged clinical applicatio
 n are outlined.</p>\n<p>Tim Gehrke</p>
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