BEGIN:VCALENDAR VERSION:2.0 PRODID:IEEE vTools.Events//EN CALSCALE:GREGORIAN BEGIN:VTIMEZONE TZID:America/New_York BEGIN:DAYLIGHT DTSTART:20260308T030000 TZOFFSETFROM:-0500 TZOFFSETTO:-0400 RRULE:FREQ=YEARLY;BYDAY=2SU;BYMONTH=3 TZNAME:EDT END:DAYLIGHT BEGIN:STANDARD DTSTART:20261101T010000 TZOFFSETFROM:-0400 TZOFFSETTO:-0500 RRULE:FREQ=YEARLY;BYDAY=1SU;BYMONTH=11 TZNAME:EST END:STANDARD END:VTIMEZONE BEGIN:VEVENT DTSTAMP:20260424T015526Z UID:F01670C8-CE2E-4F50-9F40-AF6A23106618 DTSTART;TZID=America/New_York:20260513T090000 DTEND;TZID=America/New_York:20260513T100000 DESCRIPTION:IEEE Norther Jersey Section RAS and SMC Chapter Seminar\n\nTran ssynaptic Signal Propagation and Interference for Noninvasive Modulation o f Deep Brain Activity\n\nDr. Qi (Edward) Kang\n\nDepartment of Biomedical Engineering\n\nNew Jersey Institute of Technology\n\nTime: 9am\, ECE Confe rence Room\, NJIT\n\nOnline link:\n\nhttps://njit-edu.zoom.us/j/9735966282 ?pwd=QlZtZFlOZ2FMZjlXemQwNmVUci9yUT09\n\nAbstract: Currently\, transcrania l electrical stimulation (tES) is considered one of the most widely applie d and frequently used non-invasive brain stimulation techniques. However\, within tES\, transcranial alternating current stimulation (tACS) is funda mentally limited by the rapid attenuation of electric fields with depth\, which restricts its ability to directly modulate deep brain structures. Th is talk discusses a shift from a stimulation-based perspective to a signal propagation framework\, where neural activity is controlled through trans synaptic pathways. Using in vivo recordings in anesthetized rats\, we demo nstrate that cortical tACS entrains Purkinje cells in the cerebellar corte x\, and that this activity propagates through cerebellar nuclei to modulat e neurons in the motor thalamus. The resulting responses exhibit frequency -dependent tuning\, phase locking\, and characteristic transitions between unimodal and bimodal spiking distributions\, indicating structured signal transmission across multiple synaptic stages. Building on this mechanism\ , we introduce an electrophysiological interference (EI) paradigm in which independently driven cortical inputs interact at downstream neural popula tions through synaptic integration rather than through direct electric fie ld superposition. Our results show that deep brain activity can be modulat ed in a pathway-specific and frequency-dependent manner without direct sti mulation of the target region.\n\nBiography: Qi Kang (Member\, IEEE) recei ved his B.S. degree in 2013 from Ningxia Institute of Science and Technolo gy\, M.S. degree in 2018 from New York Institute of Technology\, Ph.D. deg ree in 2025 from the New Jersey Institute of Technology. He is currently a postdoctoral researcher at NJIT in the Department of Biomedical Engineeri ng. His research focuses on noninvasive neural modulation of motor systems using electrical stimulation techniques. He has published many papers in this research areas and a frequent reviewer of several journals and confer ences.\n\nHost: Mengchu Zhou\, zhou@njit.edu\n\nNewark\, New Jersey\, Unit ed States\, Virtual: https://events.vtools.ieee.org/m/556828 LOCATION:Newark\, New Jersey\, United States\, Virtual: https://events.vtoo ls.ieee.org/m/556828 ORGANIZER:zhou@njit.edu SEQUENCE:18 SUMMARY:Seminar on Transsynaptic Signal Propagation and Interference for No ninvasive Modulation of Deep Brain Activity URL;VALUE=URI:https://events.vtools.ieee.org/m/556828 X-ALT-DESC:Description: <br /><p class="MsoNormal" align="center"><strong>I EEE Norther Jersey Section RAS and SMC Chapter Seminar</strong></p>\n<p cl ass="MsoNormal" align="center">Transsynaptic Signal Propagation and Interf erence for Noninvasive Modulation of Deep Brain Activity</p>\n<p class="Ms oNormal" align="center">Dr. Qi (Edward) Kang</p>\n<p class="MsoNormal" ali gn="center">Department of Biomedical Engineering</p>\n<p class="MsoNormal" align="center">New Jersey Institute of Technology</p>\n<p class="MsoNorma l" align="center">&nbsp\;</p>\n<p class="MsoNormal">Time: 9am\, ECE Confer ence Room\, NJIT</p>\n<p class="MsoNormal">Online link:</p>\n<p class="Mso Normal"><a href="https://njit-edu.zoom.us/j/9735966282?pwd=QlZtZFlOZ2FMZjl XemQwNmVUci9yUT09"><u>https://njit-edu.zoom.us/j/9735966282?pwd=QlZtZFlOZ2 FMZjlXemQwNmVUci9yUT09</u></a></p>\n<p class="MsoNormal"><strong>Abstract< /strong>: Currently\, transcranial electrical stimulation (tES) is conside red one of the most widely applied and frequently used non-invasive brain stimulation techniques. However\, within tES\, transcranial alternating cu rrent stimulation (tACS) is fundamentally limited by the rapid attenuation of electric fields with depth\, which restricts its ability to directly m odulate deep brain structures. This talk discusses a shift from a stimulat ion-based perspective to a signal propagation framework\, where neural act ivity is controlled through transsynaptic pathways. Using <em>in vivo</em> &nbsp\;recordings in anesthetized rats\, we demonstrate that cortical tACS entrains Purkinje cells in the cerebellar cortex\, and that this activity propagates through cerebellar nuclei to modulate neurons in the motor tha lamus. The resulting responses exhibit frequency-dependent tuning\, phase locking\, and characteristic transitions between unimodal and bimodal spik ing distributions\, indicating structured signal transmission across multi ple synaptic stages. Building on this mechanism\, we introduce an electrop hysiological interference (EI) paradigm in which independently driven cort ical inputs interact at downstream neural populations through synaptic int egration rather than through direct electric field superposition. Our resu lts show that deep brain activity can be modulated in a pathway-specific a nd frequency-dependent manner without direct stimulation of the target reg ion.</p>\n<p class="MsoNormal"><strong>Biography</strong>: Qi Kang (Member \, IEEE) received his B.S. degree in 2013 from Ningxia Institute of Scienc e and Technology\, M.S. degree in 2018 from New York Institute of Technolo gy\, Ph.D. degree in 2025 from the New Jersey Institute of Technology. He is currently a postdoctoral researcher at NJIT in the Department of Biomed ical Engineering. His research focuses on noninvasive neural modulation of motor systems using electrical stimulation techniques. He has published m any papers in this research areas and a frequent reviewer of several journ als and conferences.</p>\n<p class="MsoNormal">&nbsp\;</p>\n<p class="MsoN ormal">Host: Mengchu Zhou\, <a href="mailto:zhou@njit.edu"><u><span class= "15">zhou@njit.edu</span></u></a></p> END:VEVENT END:VCALENDAR