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DTSTAMP:20260520T172551Z
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DESCRIPTION:Whole slide images (WSIs) provide rich spatial and contextual i
 nformation for cancer diagnosis\,\nyet their gigapixel scale and susceptib
 ility to artifacts\, adversarial noise\, and distribution shifts\ncomplica
 te reliable deep learning integration. In this talk\, a unified graph-base
 d framework for\nrobust and uncertainty-aware WSI analysis is presented. T
 he proposed approach represents WSIs\nas graphs to capture spatial depende
 ncies and leverages graph neural networks (GNNs)\,\nincluding Graph Convol
 utional Networks (GCNs)\, Graph Attention Networks (GATs)\, and\nGraphSAGE
 \, for feature learning. To enhance robustness\, a denoising module\, enab
 les input-\nspecific optimization that mitigates both acquisition-related 
 artifacts (e.g.\, motion\, staining\nvariability) and adversarial perturba
 tions at image and graph levels. A transformer-based module\nfurther refin
 es global contextual modeling for accurate cancer classification across mu
 ltiple\ndatasets. To address reliability under distribution shifts\, we de
 ploy a multi-head GNN framework\nfor predictive uncertainty estimation\, w
 here head-wise divergence provides a principled measure\nof confidence and
  supports out-of-distribution detection. Extensive evaluations demonstrate
  that\nthe proposed framework significantly improves classification accura
 cy\, robustness to noise and\nattacks\, and uncertainty quantification com
 pared to conventional and non-robust methods.\n\n[Download Event Flyer](ht
 tps://events.vtools.ieee.org/event_media/download/92120)\n\n[]\n\nCo-spons
 ored by: IEEE CIS Schenectady Chapter\n\nSpeaker(s): Nasim\n\nVirtual: htt
 ps://events.vtools.ieee.org/m/557649
LOCATION:Virtual: https://events.vtools.ieee.org/m/557649
ORGANIZER:lkmestha@ieee.org, john.pole@ieee.org, murali.flute@gmail.com
SEQUENCE:218
SUMMARY:IEEE CIS &amp; CS Schenectady Chapter Technical Lecture on &quot;Robust Grap
 h-based Learning in Digital Pathology&quot;
URL;VALUE=URI:https://events.vtools.ieee.org/m/557649
X-ALT-DESC:Description: &lt;br /&gt;&lt;p&gt;Whole slide images (WSIs) provide rich spa
 tial and contextual information for cancer diagnosis\,&lt;br&gt;yet their gigapi
 xel scale and susceptibility to artifacts\, adversarial noise\, and distri
 bution shifts&lt;br&gt;complicate reliable deep learning integration. In this ta
 lk\, a unified graph-based framework for&lt;br&gt;robust and uncertainty-aware W
 SI analysis is presented. The proposed approach represents WSIs&lt;br&gt;as grap
 hs to capture spatial dependencies and leverages graph neural networks (GN
 Ns)\,&lt;br&gt;including Graph Convolutional Networks (GCNs)\, Graph Attention N
 etworks (GATs)\, and&lt;br&gt;GraphSAGE\, for feature learning. To enhance robus
 tness\, a denoising module\, enables input-&lt;br&gt;specific optimization that 
 mitigates both acquisition-related artifacts (e.g.\, motion\, staining&lt;br&gt;
 variability) and adversarial perturbations at image and graph levels. A tr
 ansformer-based module&lt;br&gt;further refines global contextual modeling for a
 ccurate cancer classification across multiple&lt;br&gt;datasets. To address reli
 ability under distribution shifts\, we deploy a multi-head GNN framework&lt;b
 r&gt;for predictive uncertainty estimation\, where head-wise divergence provi
 des a principled measure&lt;br&gt;of confidence and supports out-of-distribution
  detection. Extensive evaluations demonstrate that&lt;br&gt;the proposed framewo
 rk significantly improves classification accuracy\, robustness to noise an
 d&lt;br&gt;attacks\, and uncertainty quantification compared to conventional and
  non-robust methods.&lt;/p&gt;\n&lt;p&gt;&lt;a href=&quot;https://events.vtools.ieee.org/event
 _media/download/92120&quot; target=&quot;_blank&quot; rel=&quot;noopener&quot;&gt;Download Event Flyer
 &lt;/a&gt;&lt;/p&gt;\n&lt;p&gt;&lt;img src=&quot;https://events.vtools.ieee.org/vtools_ui/media/disp
 lay/87d171c8-cc53-4466-88e8-66fd51441302&quot; alt=&quot;&quot; width=&quot;1024&quot; height=&quot;1357
 &quot;&gt;&lt;/p&gt;
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