BEGIN:VCALENDAR VERSION:2.0 PRODID:IEEE vTools.Events//EN CALSCALE:GREGORIAN BEGIN:VTIMEZONE TZID:America/Denver BEGIN:DAYLIGHT DTSTART:20260308T030000 TZOFFSETFROM:-0700 TZOFFSETTO:-0600 RRULE:FREQ=YEARLY;BYDAY=2SU;BYMONTH=3 TZNAME:MDT END:DAYLIGHT BEGIN:STANDARD DTSTART:20261101T010000 TZOFFSETFROM:-0600 TZOFFSETTO:-0700 RRULE:FREQ=YEARLY;BYDAY=1SU;BYMONTH=11 TZNAME:MST END:STANDARD END:VTIMEZONE BEGIN:VEVENT DTSTAMP:20260819T162147Z UID:558E6A50-8D20-4BE9-9315-2CD8D408A0B8 DTSTART;TZID=America/Denver:20260910T120000 DTEND;TZID=America/Denver:20260910T130000 DESCRIPTION:Abstract: Point-of-care (POC) diagnostic devices hold great pro mise to significantly impact healthcare delivery and address health dispar ities. These devices enable a shift in focus away from the utilization of high-cost specialized care for the treatment of late-stage diseases toward predictive\, preventative\, participatory\, and personalized healthcare f or more effective disease monitoring and management. In this seminar\, Clo tChip® – a microfluidic sensor that utilizes dielectric spectroscopy fo r POC assessment of blood coagulation disorders with <10 µL of whole bloo d – will be presented. Specifically\, it will be discussed how permittiv ity measurements on microliter-range coagulating blood at MHz-range freque ncies provide clinically useful information on cellular and molecular abno rmalities in fibrin clot formation and dissolution processes. Moreover\, r esults from pilot clinical studies with ClotChip® on monitoring anticoagu lation therapy with direct oral anticoagulants (DOACs) – a new class of FDA-approved blood thinners – and coagulation factor replacement therapy in hemophilia care management will be shared. Results from correlative st udies between ClotChip® and clinically relevant global hemostatic assays such as rotational thromboelastometry (ROTEM) are also provided.\n\nSpeake r: Pedram Mohseni is the Goodrich Professor for Engineering Innovation and Inaugural Chair of the Electrical\, Computer\, and Systems Engineering De partment at Case Western Reserve University\, Cleveland\, OH\, USA. He rec eived the B.S. degree from the Sharif University of Technology\, Tehran\, Iran in 1996 and the M.S. and Ph.D. degrees from the University of Michiga n\, Ann Arbor\, MI\, USA in 1999 and 2005\, respectively\, all in electric al engineering. His main research interests are in analog/mixed-signal/RF integrated bioelectronics\, wireless power/data transfer to biomedical imp lants\, translational microfluidics\, and microassays for point-of-need di agnostics. His research activities have resulted in 2 book chapters\, over 175 refereed publications\, and 17 issued U.S. and international patents. He currently serves as the Editor-in-Chief of the IEEE Transactions on Bi omedical Circuits and Systems (TBioCAS). Dr. Mohseni has been elected a Se nior Member of the U.S. National Academy of Inventors (NAI)\, a Fellow of the American Institute for Medical and Biological Engineering (AIMBE)\, an d a Fellow of the IEEE.\n\nBldg: ICT 516\, University of Calgary\, Calgary \, Alberta\, Canada LOCATION:Bldg: ICT 516\, University of Calgary\, Calgary\, Alberta\, Canada ORGANIZER:maziar.shafieidarabi@ucalgary.ca SEQUENCE:1 SUMMARY:Prof. Pedram Mohseni: "Microfluidic Dielectric Biosensors for Point -of-Care Assessment of Hemostasis" URL;VALUE=URI:https://events.vtools.ieee.org/m/573373 X-ALT-DESC:Description: <br /><p style="text-align: justify\;"><span lang=" EN-CA"><strong>Abstract:</strong> Point-of-care (POC) diagnostic devices h old great promise to significantly impact healthcare delivery and address health disparities. These devices enable a shift in focus away from the ut ilization of high-cost specialized care for the treatment of late-stage di seases toward predictive\, preventative\, participatory\, and personalized healthcare for more effective disease monitoring and management. </span>< span lang="EN-CA">In this seminar\, ClotChip&reg\; &ndash\; a microfluidic sensor that utilizes dielectric spectroscopy for POC assessment of blood coagulation disorders with &lt\;10 &micro\;L of whole blood &ndash\; will be presented. Specifically\, it will be discussed how permittivity measure ments on microliter-range coagulating blood at MHz-</span><span lang="EN-C A">range frequencies provide clinically useful information on cellular and molecular abnormalities in fibrin clot formation and dissolution processe s. Moreover\, results from pilot clinical studies with ClotChip&reg\; on m onitoring anticoagulation therapy with direct oral anticoagulants (DOACs) &ndash\; a new class of FDA-approved blood thinners &ndash\; and coagulati on factor replacement therapy in hemophilia care management will be shared . Results from correlative studies between ClotChip&reg\; and clinically r elevant global hemostatic assays such as rotational thromboelastometry (RO TEM) are also provided.</span></p>\n<p>&nbsp\;</p>\n<p style="text-align: justify\;"><span lang="EN-CA"><strong>Speaker:</strong> </span><span lang= "EN-AU">Pedram Mohseni is the Goodrich Professor for Engineering Innovatio n and Inaugural Chair of the Electrical\, Computer\, and Systems Engineeri ng Department at Case Western Reserve University\, Cleveland\, OH\, USA. H e received the B.S. degree from the Sharif University of Technology\, Tehr an\, Iran in 1996 and the M.S. and Ph.D. degrees from the University of Mi chigan\, Ann Arbor\, MI\, USA in 1999 and 2005\, respectively\, all in ele ctrical engineering. His main research interests are in analog/mixed-signa l/RF integrated bioelectronics\, wireless </span><span lang="EN-AU">power/ data </span><span lang="EN-AU">transfer to biomedical implants\, translati onal microfluidics\, and microassays for point-of-need diagnostics. His re search activities have resulted in 2 book chapters\, over 175 refereed pub lications\, and 17 issued U.S. and international patents. He currently ser ves as the Editor-in-Chief of the IEEE Transactions on Biomedical Circuits and Systems (TBioCAS). Dr. Mohseni has been elected a Senior Member of th e U.S. National Academy of Inventors (NAI)\, a Fellow of the American Inst itute for Medical and Biological Engineering (AIMBE)\, and a Fellow of the IEEE.</span></p> END:VEVENT END:VCALENDAR