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DTSTAMP:20260928T141647Z
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DTSTART;TZID=US/Eastern:20261020T190000
DTEND;TZID=US/Eastern:20261020T200000
DESCRIPTION:From Pixels to Prognosis:\nAI\, Imaging\, and Alternative Physi
 ological Signals for Chronic Obstructive Pulmonary Disease\n\nPart I · AI
  and Quantitative Imaging for COPD Chronic obstructive pulmonary disease (
 COPD) is the third leading cause of death worldwide and remains underdiagn
 osed in more than half of affected individuals. Spirometry\, the current d
 iagnostic standard\, is insensitive to early structural change\, and quant
 itative information present in every chest CT scan is largely unexploited 
 in routine radiology practice. This talk reviews a decade of work developi
 ng artificial intelligence and quantitative imaging methods that recover d
 isease-relevant structural\, mechanical\, and textural information invisib
 le to the human eye\, drawing on validation in the COPDGene\, SPIROMICS\, 
 and National Lung Screening Trial cohorts.\n\nThe talk covers three comple
 mentary computational threads: (i) geometry-derived CT biomarkers includin
 g airway fractal dimension\, tapering\, surface-area-to-volume ratio\, and
  CT-derived dysanapsis\, all independently associated with respiratory mor
 bidity and mortality\; (ii) silent zones of lung disease\, where deep lear
 ning applied to visually normal parenchyma reveals subclinical radiomic an
 d mechanical signatures that predict emphysema onset\, exacerbation\, and 
 mortality years before conventional criteria trigger\; and (iii) deep neur
 al network analysis of raw spirometry flow-volume curves\, which recovers 
 CT-defined structural phenotype from a single breath and separates true ve
 ntilatory restriction from obstruction. The talk closes with translation o
 f these methods through UAB spin-offs and where the field is moving with v
 ision-language foundation models for multimodal chest imaging at the point
  of care.\n\nPart II · Deep Learning on the ECG for COPD Detection This t
 alk reviews recent evidence that convolutional neural networks can identif
 y COPD directly from the 12-lead electrocardiogram (ECG)\, drawing on the 
 study by Vaid et al. Because COPD produces measurable cardiopulmonary effe
 cts\, the ECG\, a ubiquitous\, low-cost\, and effort-independent signal\, 
 may carry latent information about airflow obstruction. The Mount Sinai CN
 N model was trained on 208\,231 ECGs from 18\,225 COPD cases matched to 49
 \,356 controls and evaluated on an internal holdout\, an external hospital
  cohort\, and the UK Biobank\, achieving AUC of 0.80\, 0.82\, and 0.75 res
 pectively. The talk covers the model architecture\, its linkage to concurr
 ent spirometry\, the explainability analyses identifying P-wave changes as
  the most informative ECG feature for COPD\, and how ECG-based prediction 
 could complement the imaging pipelines described in Part I and extend COPD
  screening into resource-limited settings.\n\nSpeaker(s): Kelly Powell\, M
 BA \, Sandeep Bodduluri\, MS\, PhD\n\nAgenda: \nWEBINAR: 7:00 - 8:00 P.M.\
 n\nThe Zoom Webinar link and password will be forwarded to all registered 
 participants after Noon on the day of the meeting. Check your spam folder 
 if you don&#39;t see the email.\n\nWebinar is open to all.\n\nPDH certificates
  are available and an evaluation form will be emailed to you after the mee
 ting. PDH certificate are sent by IEEE USA 3-4 weeks after the meeting.\n\
 nVirtual: https://events.vtools.ieee.org/m/579663
LOCATION:Virtual: https://events.vtools.ieee.org/m/579663
ORGANIZER:ieee@gpamg.org
SEQUENCE:58
SUMMARY:From Pixels to Prognosis: AI\, Imaging\, and Alternative Physiologi
 cal Signals for Chronic Obstructive Pulmonary Disease
URL;VALUE=URI:https://events.vtools.ieee.org/m/579663
X-ALT-DESC:Description: &lt;br /&gt;&lt;p&gt;&lt;strong&gt;&lt;span style=&quot;mso-bidi-font-weight:
  bold\;&quot;&gt;From Pixels to Prognosis:&lt;br&gt;AI\, Imaging\, and Alternative Physi
 ological Signals for Chronic Obstructive Pulmonary Disease&lt;br&gt;&lt;/span&gt;&lt;/str
 ong&gt;&lt;/p&gt;\n&lt;p class=&quot;MsoNormal&quot; style=&quot;margin: 11.0pt 0in 4.0pt 0in\;&quot;&gt;&lt;str
 ong&gt;&lt;span style=&quot;font-size: 13.0pt\;&quot;&gt;Part I&lt;span style=&quot;mso-spacerun: yes
 \;&quot;&gt;&amp;nbsp\; &lt;/span&gt;&amp;middot\;&lt;span style=&quot;mso-spacerun: yes\;&quot;&gt;&amp;nbsp\; &lt;/sp
 an&gt;AI and Quantitative Imaging for COPD&lt;span style=&quot;mso-spacerun: yes\;&quot;&gt; 
 &lt;/span&gt;&lt;/span&gt;&lt;/strong&gt;Chronic obstructive pulmonary disease (COPD) is the
  third leading cause of death worldwide and remains underdiagnosed in more
  than half of affected individuals. Spirometry\, the current diagnostic st
 andard\, is insensitive to early structural change\, and quantitative info
 rmation present in every chest CT scan is largely unexploited in routine r
 adiology practice. This talk reviews a decade of work developing artificia
 l intelligence and quantitative imaging methods that recover disease-relev
 ant structural\, mechanical\, and textural information invisible to the hu
 man eye\, drawing on validation in the COPDGene\, SPIROMICS\, and National
  Lung Screening Trial cohorts.&lt;/p&gt;\n&lt;p class=&quot;MsoNormal&quot; style=&quot;margin-bot
 tom: 6.0pt\; line-height: 120%\;&quot;&gt;The talk covers three complementary comp
 utational threads: (i) geometry-derived CT biomarkers including airway fra
 ctal dimension\, tapering\, surface-area-to-volume ratio\, and CT-derived 
 dysanapsis\, all independently associated with respiratory morbidity and m
 ortality\; (ii) &lt;em&gt;silent zones of lung disease&lt;/em&gt;\, where deep learnin
 g applied to visually normal parenchyma reveals subclinical radiomic and m
 echanical signatures that predict emphysema onset\, exacerbation\, and mor
 tality years before conventional criteria trigger\; and (iii) deep neural 
 network analysis of raw spirometry flow-volume curves\, which recovers CT-
 defined structural phenotype from a single breath and separates true venti
 latory restriction from obstruction. The talk closes with translation of t
 hese methods through UAB spin-offs and where the field is moving with visi
 on-language foundation models for multimodal chest imaging at the point of
  care.&lt;/p&gt;\n&lt;p class=&quot;MsoNormal&quot; style=&quot;margin: 11.0pt 0in 4.0pt 0in\;&quot;&gt;&lt;s
 trong&gt;&lt;span style=&quot;font-size: 13.0pt\;&quot;&gt;Part II&lt;span style=&quot;mso-spacerun: 
 yes\;&quot;&gt;&amp;nbsp\; &lt;/span&gt;&amp;middot\;&lt;span style=&quot;mso-spacerun: yes\;&quot;&gt;&amp;nbsp\; &lt;
 /span&gt;Deep Learning on the ECG for COPD Detection&lt;span style=&quot;mso-spacerun
 : yes\;&quot;&gt; &amp;nbsp\;&lt;/span&gt;&lt;/span&gt;&lt;/strong&gt;This talk reviews recent evidence 
 that convolutional neural networks can identify COPD directly from the 12-
 lead electrocardiogram (ECG)\, drawing on the study by Vaid et al. Because
  COPD produces measurable cardiopulmonary effects\, the ECG\, a ubiquitous
 \, low-cost\, and effort-independent signal\, may carry latent information
  about airflow obstruction. The Mount Sinai CNN model was trained on 208\,
 231 ECGs from 18\,225 COPD cases matched to 49\,356 controls and evaluated
  on an internal holdout\, an external hospital cohort\, and the UK Biobank
 \, achieving AUC of 0.80\, 0.82\, and 0.75 respectively. The talk covers t
 he model architecture\, its linkage to concurrent spirometry\, the explain
 ability analyses identifying P-wave changes as the most informative ECG fe
 ature for COPD\, and how ECG-based prediction could complement the imaging
  pipelines described in Part I and extend COPD screening into resource-lim
 ited settings.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;Agenda: &lt;br /&gt;&lt;p&gt;&lt;strong&gt;WEBINAR:&lt;/strong&gt;&amp;n
 bsp\;7:00 - 8:00 P.M.&amp;nbsp\;&lt;/p&gt;\n&lt;p&gt;The Zoom Webinar link and password wi
 ll be forwarded to all registered participants after Noon on the day of th
 e meeting. &lt;strong&gt;Check your spam folder if you don&#39;t see the email.&amp;nbsp
 \;&lt;/strong&gt;&lt;/p&gt;\n&lt;p&gt;Webinar is open to all.&lt;/p&gt;\n&lt;p&gt;PDH certificates are a
 vailable and an evaluation form will be emailed to you after the meeting. 
 PDH certificate are sent by IEEE USA 3-4 weeks after the meeting.&lt;/p&gt;
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