Nonlinear, Switch-like DNA Amplification for Molecular Diagnostics
The virutal event can be accessed at https://brown.zoom.us/j/94733028367
Dr. Stephanie McCalla, Assistant Professor, Department of Chemical and Biomedical Engineering, Montana State University will be presenting virtually a Biomedical Engineering Seminar co-sponsered by Brown Univerity, School of Engineering and IEEE Engineering in Medicine and Biology Society (EMBS), Providence Section.
Dr. McCalla received her BS in Bioengineering from the University of California, San Diego in 2005 and her PhD in Biomedical Engineering from Brown University in 2011. She then moved to the California Institue of Technology for a postdoctoral position in the Department of Chemistry and Chemical Engineering from 2012-2014, before starting a faculty position at Montana State University in Bozeman, Montana. Her research interests include molecular diagnostics, microfluidics, and mass transport limitations in cells and tissues.
Abstract: Switch-like reponses to stimuli are ubiquitous in nature. This switching behavior occurs in cell signaling, transcription, and genetic regulatory networks; it is commonly accepted that these switches react decisively to true signals while filtering out noise. In this seminar, Dr. McCalla will discuss novel DNA amplification chemistries with highly non-linear output: an accumulation of reaction products produces a second burst of DNA output that functions as an endogenous switch. These high-gain outputs can be applied to molecular diagnostics, DNA computing, and DNA-based logic gates.
Date and Time
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- Date: 01 Apr 2021
- Time: 11:00 AM to 12:00 PM
- All times are (GMT-05:00) US/Eastern
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- Providence, Rhode Island
- United States 02912
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- Co-sponsored by Fabiola Munarin, Brown Universtiy, School of Engineering
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- Starts 15 March 2021 08:00 AM
- Ends 01 April 2021 01:00 PM
- All times are (GMT-05:00) US/Eastern
- No Admission Charge