Information Content of High-order Associations of the Human Gut Microbiota Network
University of Pittsburgh, Health Informatics Grand Rounds (Free Webinar) | August, 19th, 2022, 12 to 1:00pm EDT
Co-sponsored by IEEE Computer Society at Pittsburgh
Abstract: The human gastrointestinal tract is an environment that hosts an ecosystem of microorganisms essential to human health. Vital biological processes emerge from fundamental inter- and intra-species molecular interactions that influence the assembly and composition of the gut microbiota ecology. We quantify the complexity of the ecological relationships within the human infant gut microbiota ecosystem as a function of the information contained in the nonlinear associations of a sequence of increasingly-specified maximum entropy representations of the system. Our paradigm frames the ecological state, in terms of the presence or absence of individual microbial ecological units that are identified by amplicon sequence variants (ASV) in the gut microenvironment, as a function of both the ecological states of its neighboring units and, in a departure from standard graphical model representations, the associations among the units within its neighborhood. We characterize the order of the system based on the relative quantity of statistical information encoded by high-order statistical associations of the infant gut microbiota.
Guest Speaker:
Prof. Weston Viles, PhD
Khoury College of Computer Science
The Roux Institute
Northeastern University
Date and Time
Location
Hosts
Registration
- Date: 19 Aug 2022
- Time: 12:00 PM to 01:00 PM
- All times are (UTC-04:00) Eastern Time (US & Canada)
-
Add Event to Calendar
- Contact Event Host
-
Contacts:
Vishal Rastogi, Chair, IEEE Computer Society, Pittsburgh; vishal.ras@gmail.com
Ahmad P. Tafti, Vice Chair, IEEE Computer Society, Pittsburgh; apt33@pitt.edu
- Co-sponsored by The University of Pittsburgh, School of Health and Rehabilitation Sciences, Department of Health Information Management
- Starts 14 August 2022 10:34 AM
- Ends 19 August 2022 11:30 AM
- All times are (UTC-04:00) Eastern Time (US & Canada)
- No Admission Charge
Speakers
Prof. Weston Viles, PhD
Biography:
Dr. Viles earned a Ph.D. in Mathematics from the Department of Mathematics and Statistics at Boston University with a thesis titled "Network Data Analysis". He subsequently completed postdoctoral training in the Department of Biomedical Data Science at Dartmouth College. His research objective is to further develop the theory and methods of network data analysis from its statistical foundations to applications in natural systems. His attention toward network inference and characterization aims to quantify and distinguish aspects of the statistical associations among entities in complex systems to gain knowledge of the system as a whole. His recent work has focused on developing network-based predictors in the context of health-related applications in areas of neuroscience and epidemiology. Information content of high-order associations of the human gut microbiota network.
Khoury College of Computer Science
The Roux Institute
Northeastern University
Agenda
The Health Informatics Grand Rounds at the University of Pittsburgh, School of Health and Rehabilitation Sciences is a publicly and freely available seminar series which mainly aims to offer a professional forum for health data scientists to present their latest research findings and scientific innovations. Looking forward to seeing you there!
Registration (Free):
Please register here!
Date/Time:
Friday, August 19th, 2022: 12 to 1:00pm EDT
Virtual Event (Zoom)