[Legacy Report] LINCS Canvas Browser: interactive web app to query, browse and interrogate L1000 gene expression signatures
#"INCS
#Canvas
#Browser:
#interactive
#web
#app
#to
#query
#browse
#and
#interrogate
#L1000
#gene
#expression
#signatures"
#Dr.
#Avi
#Ma’ayan
#Icahn
#School
#of
#Medicine
#at
#Mount
#Sinai.
For the NIH project LINCS, gene expression profiles were collected from many human cancer cell-lines responding to thousands of chemical and genetic perturbations for a total of over one million experiments. Visualizing and analyzing such large dataset for biological knowledge extraction is challenging. The LINCS Canvas Browser (LCB) is an interactive HTML5 web-based application that facilitates querying, browsing and interrogating almost all currently available LINCS gene expression data. LCB implements two compacted layered canvases, one to visualize clustered experiments and the other to display enrichment analysis results.
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