[Legacy Report] Microfluidic devices with integrated structured electrodes for on-chip sensing

#Microfluidics

The development of widely applicable point-of-care sensing and diagnostic devices can benefit from simple and inexpensive fabrication techniques that expedite the design, testing, and implementation of lab-on-a-chip devices. In particular, electrodes integrated within microfluidic devices enable the use of electrochemical techniques for the label-free detection of relevant analytes. This work presents a novel, simple, and cost-effective bench-top approach for the integration of high surface area three-dimensional structured electrodes fabricated on polystyrene (PS) within poly(dimethylsiloxane) (PDMS)-based microfluidics. The fabrication and bonding processes are shown to have no effect on sensing electrode performance. Two configurations of three-electrode electrochemical cell are tested, and a salt bridge-free configuration is used for sensing. Finally, the on-chip sensing capabilities of the electrochemical cell are demonstrated with a model redox compound, where the high surface area structured electrodes exhibit ultra-high sensitivity. We propose that the developed approach can significantly expedite and reduce the cost of fabrication of sensing devices where arrays of functionalized electrodes can be used for point-of-care analysis and diagnostics.

• Date: 20 Jun 2017
• Time: 04:00 PM to 05:00 PM
• All times are (GMT-05:00) Canada/Eastern
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• Quebec City, Quebec
• Canada

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