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Seminar:Microwaving a Biological Cell Alive ‒ Label-free Noninvasive Cell Characterization by Broadband Impedance Spectroscopy
Seminar
Microwaving a Biological Cell Alive ‒Label-free Noninvasive Cell Characterization by Broadband Impedance Spectroscopy
Professor James C. M. Hwang
Cornell University, Ithaca, New York, USA
Date : 25 November 2022 (Friday)
Time : 11:00am – 12:00 noon
Onsite (with limited seats) is for City University of Hong Kong (CityU) staff and students only
Online (Zoom) for the participants outside CityU
Venue: Room 15-202, 15/F, Lau Ming Wai Academic Building, CityU (Lift 1 or 2)
Registration: https://events.vtools.ieee.org/event/register/331969
Microwave is not just for cooking, smart cars, or mobile phones. We can take advantage of the wide electromagnetic spectrum to do wonderful things that are more vital to our lives. For example, microwave ablation of cancer tumor is already in wide use, and microwave remote monitoring of vital signs is becoming more important as the population ages. This talk will focus on a biomedical use of microwave at the single-cell level. At low power, microwave can readily penetrate a cell membrane to interrogate what is inside a cell, without cooking it or otherwise hurting it. It is currently the fastest, most compact, and least costly way to tell whether a cell is alive or dead. On the other hand, at higher power but lower frequency, the electromagnetic signal can interact strongly with the cell membrane to drill temporary holes of nanometer size. The nanopores allow drugs to diffuse into the cell and, based on the reaction of the cell, individualized medicine can be developed and drug development can be sped up in general. Conversely, the nanopores allow strands of DNA molecules to be pulled out of the cell without killing it, which can speed up genetic engineering. Lastly, by changing both the power and frequency of the signal, we can have either positive or negative dielectrophoresis effects, which we have used to coerce a live cell to the examination table of Dr. Microwave, then usher it out after examination. These interesting uses of microwave and the resulted fundamental knowledge about biological cells will be explored in the talk.
Date and Time
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- City University of Hong Kong
- Hong Kong, Hong Kong
- Hong Kong
- Building: Lau Ming Wai Academic Building
- Room Number: Room 15-202, 15/F
- Starts 10 November 2022 05:00 AM UTC
- Ends 25 November 2022 10:00 AM UTC
- No Admission Charge
Speakers
Microwaving a Biological Cell Alive ‒ Label-free Noninvasive Cell Characterization by Broadband Impedance Spectroscopy
James Hwang is a professor in the Department of Materials Science and Engineering at Cornell University. He graduated from the same department with a Ph.D. degree. After years of industrial experience at IBM, Bell Labs, GE, and GAIN, he spent most of his academic career at Lehigh University. He cofounded GAIN and QED; the latter became the public company IQE and remains the world's largest compound-semiconductor epitaxial wafer supplier. He used to be a Program Officer at the U.S. Air Force Office of Scientific Research for GHz-THz Electronics. He had been a visiting professor at Cornell University in the US, Marche Polytechnic University in Italy, Nanyang Technological University in Singapore, National Chiao Tung University in Taiwan, and Shanghai Jiao Tong University in China. He is an IEEE Life Fellow and a Distinguished Microwave Lecturer. He is also a Track Editor for the IEEE Transactions on Microwave Theory and Techniques. He has published approximately 400 refereed technical papers and been granted ten U.S. patents. He has researched the design, modeling and characterization of optical, electronic, and micro-electromechanical materials, devices, and circuits. His current research interest focuses on high-frequency (> 110 GHz) devices and circuits for 6G wireless communications and other applications.