Enabling techniques for tissue characterization using ultrasound Hermite-scan imaging and shear wave viscoelastography
Ultrasound is rapidly evolving and can now provide information about tissue structure and stiffness for enabling objective diagnosis. Hermite-scan (H-scan) imaging is a new approach for characterizing tissue structures based on color-mapping of scatterer sizes. In H-scan imaging, radiofrequency (RF) echoes are matched to Gaussian-weighted Hermite polynomials of order n, which are related to the size of scatterers. Furthermore, shear wave viscoelastography exploits the shear wave generated by an ultrasound beam and extracts the viscoelastic properties of tissues from the frequency dependence of the measured wave velocity. In this talk, I will demonstrate the feasibility of differentiating glioblastoma tumors from normal brain tissue ex vivo using H-scan imaging, with potential applications in intraoperative brain tumor imaging. I will also discuss our work on validating shear wave viscoelastography on viscoelastic tissue-mimicking phantoms.
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- Date: 15 Jul 2023
- Time: 07:00 PM to 08:00 PM
- All times are (UTC+05:30) Chennai
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- Starts 13 July 2023 05:00 PM
- Ends 15 July 2023 01:00 PM
- All times are (UTC+05:30) Chennai
- No Admission Charge
Speakers
Dr. Karla Mercado-Shekhar of Indian Institute of Technology (IIT) Gandhinagar
Enabling techniques for tissue characterization using ultrasound Hermite-scan imaging and shear wave viscoelastography
Ultrasound is rapidly evolving and can now provide information about tissue structure and stiffness for enabling objective diagnosis. Hermite-scan (H-scan) imaging is a new approach for characterizing tissue structures based on color-mapping of scatterer sizes. In H-scan imaging, radiofrequency (RF) echoes are matched to Gaussian-weighted Hermite polynomials of order n, which are related to the size of scatterers. Furthermore, shear wave viscoelastography exploits the shear wave generated by an ultrasound beam and extracts the viscoelastic properties of tissues from the frequency dependence of the measured wave velocity. In this talk, I will demonstrate the feasibility of differentiating glioblastoma tumors from normal brain tissue ex vivo using H-scan imaging, with potential applications in intraoperative brain tumor imaging. I will also discuss our work on validating shear wave viscoelastography on viscoelastic tissue-mimicking phantoms.
Biography:
Dr. Karla Mercado-Shekhar is an Assistant Professor in Biological Engineering and the Co-coordinator for the Centre of Biomedical Engineering at IIT Gandhinagar. She received her Bachelors degree in Biomedical Engineering from Boston University, U.S.A., and her Masters and Ph.D. in Biomedical Engineering from the University of Rochester, U.S.A., as a Provost’s Fellow. She was a Postdoctoral Fellow at the University of Cincinnati College of Medicine and a recipient of a postdoctoral research grant from the U.S.A. National Institutes of Health. Dr. Mercado-Shekhar joined IIT Gandhinagar in 2019, and co-leads the Medical Ultrasound Engineering (MUSE) Lab, which focuses on developing and translating ultrasound techniques to aid in the diagnosis, treatment, and management of diseases. She serves in the Technical Program Committee of the IEEE International Ultrasonics Symposium, the Biomedical Acoustics Technical Committee of the Acoustical Society of America, and the Advisory Editorial Board of the journal Ultrasound in Medicine and Biology.
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