IEEE Microsystems Tech Talk: Integrating computational and hardware approaches for ultradeep Optical Coherence Tomography (OCT)
Key factors that limit imaging depth of optical coherence tomography (OCT) are signal-to-noise ratio (SNR) and multiple scattering (MS). In the first part of the talk, I will discuss a long-wavelength (1600 nm) balanced spectral-domain approach that includes coherent averaging of measurements to improve SNR of weak signals from deep within scattering samples. With this approach, we show that imaging beyond 3 mm (optical depth) in scattering tissues (chicken breast and mouse brain; ex vivo), is possible. In the second part of the talk, I will discuss our aberration-diverse OCT (AD-OCT) approach to suppress MS signal contributions from deep within scattering media. AD-OCT performs multiple measurements, each with a different aberration state of the imaging beam (to randomize the MS contribution across measurements). Computational adaptive optics (CAO) is then used to mitigate the resolution penalty normally associated with these aberrations, followed by coherent averaging to enhance the ballistic-photon contribution to the OCT signal. MS suppression with AD-OCT is demonstrated via imaging a USAF-target placed deep within scattering media.
Speaker:
Dr. Steven Adie, Associate Professor at Cornell University
Biomedical Optics and Biophotonics Imaging
Dr. Adie completed a BSc with First Class Honours in Chemical Physics in 1997 and earned a PhD in Electrical and Electronic Engineering (specializing in Biomedical Optics) in 2007, both from The University of Western Australia. Between his undergraduate and graduate studies he worked as a Research Engineer at Q-Vis Limited – a startup company to commercialize solid-state laser technology for LASIK eye surgery. After completing his PhD, he did a postdoc in the Biophotonics Imaging Laboratory at the Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign. In 2013 he started as an Assistant Professor in the Meinig School of Biomedical Engineering, where his group develops novel optical coherence elastography and computational optical coherence microscopy approaches for mechanobiology and neuroscience research. Dr. Adie is the recipient of the NSF CAREER Award, NIBIB Trailblazer Award, and the Cornell Discovery and Innovation Research Seed Award.
Email: sga42@cornell.edu
Date and Time
Location
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Registration
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- 147 S Bedford St
- Burlington, Massachusetts
- United States 01803
- Building: Building V Conference Hall
- Starts 30 July 2025 04:00 AM UTC
- Ends 12 August 2025 04:00 AM UTC
- No Admission Charge
Speakers
Steve Adie
Integrating computational and hardware approaches for ultradeep Optical Coherence Tomography (OCT)
Steven Adie (Associate Professor)
Biomedical Optics and Biophotonics Imaging
Dr. Adie completed a BSc with First Class Honours in Chemical Physics in 1997 and earned a PhD in Electrical and Electronic Engineering (specializing in Biomedical Optics) in 2007, both from The University of Western Australia. Between his undergraduate and graduate studies he worked as a Research Engineer at Q-Vis Limited – a startup company to commercialize solid-state laser technology for LASIK eye surgery. After completing his PhD, he did a postdoc in the Biophotonics Imaging Laboratory at the Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign. In 2013 he started as an Assistant Professor in the Meinig School of Biomedical Engineering, where his group develops novel optical coherence elastography and computational optical coherence microscopy approaches for mechanobiology and neuroscience research. Dr. Adie is the recipient of the NSF CAREER Award, NIBIB Trailblazer Award, and the Cornell Discovery and Innovation Research Seed Award.
Email: sga42@cornell.edu
Biography:
Dr. Adie completed a BSc with First Class Honours in Chemical Physics in 1997 and earned a PhD in Electrical and Electronic Engineering (specializing in Biomedical Optics) in 2007, both from The University of Western Australia. Between his undergraduate and graduate studies he worked as a Research Engineer at Q-Vis Limited – a startup company to commercialize solid-state laser technology for LASIK eye surgery. After completing his PhD, he did a postdoc in the Biophotonics Imaging Laboratory at the Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign. In 2013 he started as an Assistant Professor in the Meinig School of Biomedical Engineering, where his group develops novel optical coherence elastography and computational optical coherence microscopy approaches for mechanobiology and neuroscience research. Dr. Adie is the recipient of the NSF CAREER Award, NIBIB Trailblazer Award, and the Cornell Discovery and Innovation Research Seed Award.
Agenda
6-6:45 PM EDT - Networking Dinner
6:45 - 7:45PM EDT - TechTalk and Q&A