Location, Location, Location – Site-Selective Interactions at the Molecular Scale
A hallmark of Nanoscience is the variety of wonderful new properties of matter when it is reduced to nanometer dimensions. Scientists and engineers around the world are working hard to exploit these properties in a broad range of applications, ranging from electronics to energy, as well as biology and medicine. One of the great challenges in this effort is controlling the organization of such small objects. We are presently exploring strategies which combine traditional lithographic patterning with new surface chemistries and biomolecular assembly to control the placement of individual molecules and electronically functional nanostructures over macroscopic dimensions. One direction we are pursuing involves lithographically directed DNA assembly. In this approach, we bind DNA molecules and DNA nanostructures to molecular-scale anchors on a surface in a way that retains the DNA shape and function. This provides a platform to study biomolecular interactions and to explore ways in which DNA can be used to organize the assembly of electronically and optically functional nanostructures, such as carbon nanotubes, semiconductor nanowires and quantum dots, in order to take full advantage of their unique properties. We use a similar approach to create biomimetic surfaces which simulate specific physical properties of the extracellular matrix down to the single-molecule level. Developing an understanding of the factors required to elicit a given cellular response will yield insight into the functional complexes involved in specific cell behaviors and how these may be altered. Potential applications range from therapeutic treatments that block metastasis to the rational design of tissue scaffolds that can optimize healing without scarring.
Date and Time
Location
Hosts
Registration
-
Add Event to Calendar
- 164 Warren St
- Newark, New Jersey
- United States 07102
- Building: Electrical and Computer Engineering
- Room Number: ECE202
- Contact Event Host
- Prof. H. Grebel e-mail: grebel@njit.edu
- Starts 27 October 2011 08:00 PM UTC
- Ends 27 October 2011 09:00 PM UTC
- No Admission Charge
Speakers
Dr. Shalom Wind
Location, Location, Location – Site-Selective Interactions at the Molecular Scale
Biography: Shalom J. Wind received his B.A. degree in Physics from Yeshiva University and his M.Phil. and Ph.D. degrees in Physics from Yale University. He joined IBM’s Thomas J. Watson Research Center in 1987, following his doctoral studies. As a member of the Silicon Technology Department, his work there focused primarily on the fabrication and study of nanostructures and nanodevices and the scaling of silicon transistors to smaller dimensions. Since joining the Department of Applied Physics and Applied Mathematics at Columbia University in 2003, Wind’s research has focused on the development of new techniques for creating structures at the scale of individual molecules and applications thereof in the physical and life sciences, including electron transport through single molecules, directed DNA assembly of functional nanostructures and engineering functional biomolecular systems for the fundamental study of cell behavior. Wind is a senior member of the IEEE.
Address:Columbia University, , New York, United States
Dr. Shalom Wind
Location, Location, Location – Site-Selective Interactions at the Molecular Scale
Biography:
Address:New York, United States